Archive : Winter 2006

Infographic //
Making Markets for Vaccines

Nothing spurs innovation like the promise of profits, which motivates pharmaceutical companies to spend the hundreds of millions of dollars necessary to develop a single drug. As drugmakers devote their efforts to curing diseases of aging, for which there are lucrative markets in wealthy countries, the poorest countries are forgotten. Only 10% of global spending on drug development goes toward prevention and treatment for ailments that affect 90% of the world's population. Such brutal economics have hindered the search for vaccines against HIV/AIDS, malaria and tuberculosis, which each year kill approximately 5 million people.





The World's Greatest Killers
Disability-adjusted life years (years lost to premature mortality and disability) tell the story: While communicable conditions take an awesome toll in the poorest countries, diseases of aging, including cancer and heart disease, are of greater concern in affluent countries.






The Vaccine Divide
In terms of medicine R & D, the poorest countries are largely ignored.






The Beleaguered Bottom Line
For drug companies looking to develop vaccines for the poorest countries, the economics are bleak.
There are simply few profits to be had.






Market Forces to the Rescue
In an approach called advance market commitments, rich countries would promise to pay for vaccine dosages on behalf of the poorest countries — providing to drug companies the incentive to devote R & D to poor-country diseases. G7 finance ministers have agreed to a pilot program based on a proposal by the Center for Global Development, a Washington, D.C., think tank that seeks commitments of approximately $3 billion each for HIV/AIDS, tuberculosis and malaria.




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Infographic by Grundy & Northedge

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